Drops Manufacturer/Distributor: Aristopharma Limited Generic Name: Olopatadine 0.2% Eye Drops
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Indications
Olopatadine is used to relieve itchiness in the eyes caused by allergic conjunctivitis.
Pharmacology
Olopatadine is an inhibitor of the release of histamine from the mast cell and a relatively selective histamine H1‐antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine-induced effects on human conjunctival epithelial cells. Olopatadine is devoid of effects on alpha-adrenergic, dopamine, and muscarinic type 1 and 2 receptors. Olopatadine was found to have minimal systemic exposure after topical ocular application in humans.
Dosage & Administration
0.1% Sterile Eye Drops: One drop in each affected eye two times per day at an interval of 6 to 8 hours.
0.2% Sterile Eye Drops: One drop in the affected eye once a day.
0.7% Sterile Eye Drops: One drop in each affected eye once a day.
Interaction
It's possible that CNS depressants will cause additive CNS depression.
Contraindications
Olopatadine Hydrochloride ophthalmic solution is not recommended for people who have a known hypersensitivity to the drug.
Side Effects
Headaches have been observed to affect 7% of people. In less than 5% of patients, the following negative experiences were reported: Asthenia, blurred vision, burning or stinging, cold syndrome, dry eye, foreign body sensation, hyperemia, hypersensitivity, keratitis, lid edema, nausea, pharyngitis, pruritus, rhinitis, sinusitis, and taste perversion are all symptoms of asthenia, pharyngitis, pruritus, rhinitis, sinusitis, and taste perversion.
Pregnancy & Lactation
In pregnant women, there are no sufficient and well-controlled trials. Because animal studies do not always predict human reactions, this medicine should only be given to pregnant women if the potential benefit to the mother outweighs the risk to the fetus.
It's unclear whether topical ocular treatment would cause enough systemic absorption to create measurable amounts in human breast milk. When administering Olopatadine Hydrochloride ophthalmic solution to a nursing mother, however, caution should be exercised.
Precautions & Warnings
Contact lens irritation should not be treated with olopatadine HCl ophthalmic solution. Soft contact lens wearers should be told to wait at least ten minutes after infusing Olopatadine Hydrochloride ophthalmic solution before putting their lenses in.
Storage Conditions
Store below 30° C in a cold, dry, and light-protected location. Keep out of children's reach. Because touching the dropper tip to surfaces can contaminate the solution, avoid doing so. After 30 days from the date of initial opening, do not use.
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